The aim o f this book is to review all the hematological changes and interactions in malaria and, in so doing, to emphasize the importance of malaria a s a primarily hematological disease and to increase the awareness and interest amongst hematologists, malariologists and tropical physicians.
Modern Hematology: Biology and Clinical Management
Reinhold Munker, Erhard Hiller, Jonathan Glass, and Ronald Paquette
Reinhold Munker and his distinguished colleagues have updated and expanded Modern Hematology: Biology and Clinical Management, now in its second edition, to reflect the major advances in the understanding, diagnosis, and treatment of blood disorders. Modern Hematology: Biology and Clinical Management, Second Edition describes the latest clinical and scientific developments, including molecular studies used to diagnose a variety of hematological disorders and guide their treatment. Targeted and molecular therapies are discussed in detail, including kinase inhibitors in myeloproliferative disorders and humanized monoclonal antibodies. The use of peripheral blood and umbilical cord blood stem cells for transplantation is described, as well as the rationale and indications for non-myeloablative transplantation, emphasizing the preferability of immunotherapy over cytotoxic chemotherapy.
From Local Invasion to Metastatic Cancer: Involvement of Distant Sites Through the Lymphovascular System
(Current Clinical Oncology)
Stanley P. L. Leong
In human solid tumors, nodal status is the most important prognostic indicator for patient outcome. Recent developments in the sentinel lymph node concept have resulted in new procedures to define the first draining node as the primary gateway through which the cancer will spread. In From Local Invasion to Metastatic Cancer: Involvement of Distant Sites Through the Lymphovascular System, a panel of international authorities takes an in-depth look at the role of the lymphovascular system in the spread of cancer. The authors summarize the findings of the Second International Symposium on Cancer Metastasis: Basis for Rational Therapy summit. Specifically, the book presents important developments in the biology and clinical understanding of cancer metastasis, describes the relationship between tumor microenvironment and proliferation, and defines the process of lymphangiogenesis and angiogenesis with special reference to cancer metastasis. From Local Invasion to Metastatic Cancer: Involvement of Distant Sites Through the Lymphovascular System provides oncologists, radiologists, and cancer researchers the necessary information to study and develop new strategies to curb the process of metastasis.
John P Greer, John Foerster, George M Rodgers, and Frixos Paraskevas
Lippincott Williams & Wilkins
Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology continues to be an industry leader with its ability to correlate basic science with the clinical practice of hematology. With the first edition of Wintrobe's Clinical Hematology published in 1942 clearly establishing hematology as a distinct subspecialty of Internal Medicine, the latest edition continues the influence of the Wintrobe name and helps to set this book apart from the competition. With its strong focus on the clinical aspects of hematology, the book has generated a strong following among internists and general practitioners who want a single resource to consult for their patients who present any blood related disorder. The Twelfth Edition is in full color for the first time, boasts a new editorial team, and includes expanded coverage of new medications and four new chapters on Newborn Anemias, Pathology of LHC, Spleen Tumors, and Myeloproliferative Disorders and Mast Cell Disease. A companion Website will offer the fully searchable text and an image bank.
Although the means of diagnosing and treating fungal infections have improved greatly over the last decade fungi still represent a serious threat to the health of immunocompromised and immunodeficient patients. The aim of this book is to give an in-depth assessment of our current understanding of the Biology of the main fungal pathogens and how they interact with the host s immune response. Each Chapter focuses on a specific fungal pathogen or group of pathogens and examines their biology and the factors that allow the fungus colonise and disseminate within the host. In addition each Chapter gives an indication of the challenges that remain to be tackled over the next 5 10 years in increasing our understanding of fungal pathogenicity. Each chapter is written by internationally recognized experts and this has ensured that the book is as comprehensive and authoritative a text as is possible to assemble.
M.I.N.D. (Metabolic Irregularities Narrowing down Device). This is all-in one intelligent medical calculator, acid-base and electrolyte analyzer with artificial intelligence differential diagnosis capabilities (and stratification based on a diagnosis score).