Thursday, May 31, 2012

Artifacts in Histological and Cytological Preparations

Artifacts in Histological and Cytological Preparations
Geoffrey O Rolls BAppSc, Neville J Farmer, John B Hall,

In histological and cytological terms an artifact can be defi ned as a structure that is not normally present in the living tissue. The problem is recognizing artifacts as such when they do occur and not confusing them with normal tissue components or pathological changes. In some situations the presence of an artifact can compromise an accurate diagnosis.
The aim of this publication is to promote an awareness of the various artifacts which may be encountered in histopathology, to provide a guide for their recognition, to explain their causes and to suggest, where possible, the means by which their occurrence can be avoided. Examples of many common ar t i fact s and some rare ones have been included but t he intent ion is t o provide an over view of artifacts and not a complete compendium. Alternative names for the artifacts are included in the list of common artifacts on page 100.



Wednesday, May 30, 2012

Platelets in Thrombotic and Non-thrombotic Disorders: Pathophysiology, Pharmacology and Therapeutics, 1st ed, 2002


Platelets in Thrombotic and Non-thrombotic Disorders-
Pathophysiology, Pharmacology and Therapeutics,
Paolo Gresele, Clive P. Page, Valentin Fuster, Jos Vermylen
ISBN-10: 052180261X
ISBN-13: 978-0521802611

This book reviews current science and applications of platelets research in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis and therapeutics of diseases involving platelets. Chapters are devised to provide a critical review of the most clinically relevant aspects of the subject.



Male Infertility: Diagnosis and Treatment, 1st ed. 2007

Male Infertility: Diagnosis and Treatment
Thinus F. Kruger and Sergio Oehninger
ISBN-10: 0415397421
ISBN-13: 978-0415397421

Male factor infertility is a common problem in reproductive medicine and can have a significant effect of the outcome of IVF treatment. This comprehensive book covers the diagnosis and treatment of male factor infertility in depth. It opens with a section on the basic science underlying the production of male gametes. There is then a major section on diagnosis that will prove very useful to a wide range of andrologists, endocrinologists, and REIs faced with unpicking the problems facing infertile couples. The final section addresses management of the subfertile male, including endocrinologic, surgical, and ART interventions. The book is authored by a prestigious, international team of contributors.



Tuesday, May 29, 2012

A Handbook for Medical Teachers, 4th ed. 2002

A Handbook for Medical Teachers
D. I. Newble and R. A. Cannon
ISBN-10: 9048157420
ISBN-13: 978-9048157426

This is the extensively revised 4th edition of a popular handbook It offers a successful combination of sound educational principles, a how-to-do-it approach and an entertaining easy-to-read style, and contains numerous illustrations, examples, and pertinent cartoons. This fourth edition has been revised to reflect the major changes that continue to occur in both undergraduate and postgraduate education.



Monday, May 28, 2012

Pathology of Vascular Skin Lesions: Clinicopathologic Correlations, 2003

Pathology of Vascular Skin Lesions: Clinicopathologic Correlations, 2003
Omar P. Sangüeza and Luis Requena
ISBN-10: 1617374075
ISBN-13: 978-1617374074

A comprehensive review of all the vascular proliferations involving the skin and subcutaneous tissue, including recently described disease entities. Superbly illustrated with both clinical and histopathologic photographs, the book moves from a proposed new system of classification and nomenclature for vascular neoplasms, to a full discussion of benign and malignant proliferations, including hamartomas, benign neoplasms, malignant neoplasms, and several related newly reported diseases. The authors describe in-depth the clinical and morphologic aspects of each entity and detail their clinicopathologic correlation, differential diagnosis, prognosis, and therapy.



Sunday, May 27, 2012

Tumors and Tumor-like Conditions of the Lung and Pleura, 1st ed. 2010

Tumors and Tumor-like Conditions of the Lung and Pleura
Cesar A. Moran MD and Saul Suster
ISBN-10: 1416036245
ISBN-13: 978-1416036241

Tumors and Tumor-like Conditions of the Lung and Pleura is a superb visual resource that brings the state-of-the-art in thoracic diagnosis straight to the lab bench. Cesar A. Moran and Saul Suster are internationally recognized experts in pulmonary pathology who present a coherent and consistent approach to interpretation and diagnosis. Through more than 900 stunning photographs and a consistent, user-friendly format, this resource provides quality guidance on the diagnostic problems you face in everyday practice. You'll get a host of innovative, practice-oriented features unavailable in any other text that streamline and facilitate diagnostic decision-making. Written by practitioners for practitioners, this visual resource is designed for quick and easy use. You can't afford to be without it.
  • Features over 900 high-quality full-color illustrations so you can recognize and diagnose any tissue sample under the microscope.
  • Presents immunohistochemical and genetic features wherever relevant for comprehensive information on all of the investigative contexts important to formulating an accurate diagnosis.
  • Includes summary tables throughout the text to simplify and clarify complex discussions and enable "at a glance" comparisons between entities.
  • Provides practical advice from experts on pitfalls in differential diagnosis to help you avoid diagnostic errors.



Wednesday, May 23, 2012

Molecular Pathogenesis of MODYs, 1st ed. 2000

Molecular Pathogenesis of MODYs
American Diabetes Association Symposium. Scottsdale, Ariz., Usa, November 6-8, 1998
M. A. Magnuson and F. M. Matschinsky
ISBN-10: 3805569505
ISBN-13: 978-3805569507

A timely collection of research papers by 18 leading scientists in the area of biochemical genetics of diabetes mellitus, these contributions focus on a well defined class of monogenic forms of the disease (i.e. MODYs 1-5) all caused by specific mutations or deletion of genes that control pancreatic beta-cell functions: HNF-4alpha, glucokinase, HNF-1alpha, IDX-1 and HNF-1beta. This volume offers a historical perspective of MODYs, and it also contains contributions which deal with the fundamental questions of pancreas and liver development, critical for the understanding of the syndrome complex discussed. Attempts have been made to highlight results and concepts that may be relevant for understanding type-II diabetes in general, exemplified by contributions that connect the field of pancreatic islet cell biology and pathology with the newest findings in the area of insulin action, e.g. the role of the insulin receptor and insulin receptor substrates (IRS 1-3).

Tuesday, May 22, 2012

Bone and Soft Tissue Pathology : Foundations in Diagnostic Pathology Series, 1st ed, 2010

Bone and Soft Tissue Pathology
A Volume in the series, Foundations in Diagnostic Pathology
by Andrew L. Folpe, Carrie Y. Inwards.
ISBN: 978-0-443-06688-7

This book is primarily intended to be a day-to-day supplement to larger and more comprehensive bone and soft tissue pathology textbooks. It provides upto-date information on the surgical pathology of bone and soft tissue and emphasizes practical diagnostic aspects. These are addressed with more than 600 high-quality, full-color illustrations, as well as numerous boxes and tables to enhance and facilitate the presentation of information.



Monday, May 21, 2012

Clinical Aspects and Laboratory. Iron Metabolism, Anemias: Concepts in the anemias of malignancies and renal and rheumatoid diseases, 6th ed. 2011

Clinical Aspects and Laboratory. Iron Metabolism, Anemias: Concepts in the anemias of malignancies and renal and rheumatoid diseases
Manfred Wick, Wulf Pinggera and Paul Lehmann
ISBN-10: 3709100860
ISBN-13: 978-3709100868

Iron is essential for most forms of life, including humans. On the other hand, iron is also potentially toxic. Therefore, the control of iron metabolism and maintenance of iron hemostasis is an crucial part of many aspects of human health and disease. Iron deficiency anemia is one of the most common diseases worldwide, but there are also anemias associated with chronic diseases, and other acquired or hereditary defects. Understanding the control of iron metabolism is furthermore important for understanding diseases of iron overload, like hemochromatosis. This booklet is designed for physicians, clinical lab personnel and medical students. It gives an overview about the principles of regulation of iron metabolism and erythropoiesis. In addition, the various disturbances of iron metabolism and the associated clinical findings are described. Special focus lies on the differential diagnosis of the disorders, and the approaches of therapy. Finally, a comprehensive schedule of tests is included available for the determination of iron metabolism-related parameters in serum/plasma and blood, with indication of methodologies applied and reference ranges.

Sunday, May 20, 2012

Color Atlas of Genetics, 3rd ed. 2007


Color Atlas of Genetics, 3rd ed. 2007
Eberhard Passarge,

The aim of this book is to give an account of the scientific field of genetics based on visual displays of selected concepts and related facts. Additional information is presented in the introduction, with a chronological list of important discoveries and advances in the history of genetics, in an appendix with supplementary data in tables, in an extensive glossary explaining genetic terms, and in references, including web sites for further in-depth studies.



Saturday, May 19, 2012

Surgical Pathology of Endocrine and Neuroendocrine Tumors, 1st ed. 2009

Surgical Pathology of Endocrine and Neuroendocrine Tumors
(Current Clinical Pathology)
Ashraf Khan
ISBN-10: 1603273956
ISBN-13: 978-1603273954

Surgical pathology is the cornerstone in the management of neoplastic disorders. Written for the practicing surgical pathologist in mind, Surgical Pathology of Endocrine and Neuroendocrine Tumors provides an up-to-date text on surgical pathology of endocrine and neuroendocrine tumors. The text begins with radiological imaging of tumors, followed by a section on fine needle aspiration biopsy. The main section focuses on surgical pathology of endocrine and neuroendocrine tumors. The volume closes with applications of molecular techniques and their potential for the future. Surgical Pathology of Endocrine and Neuroendocrine Tumors is written by a panel of internationally recognized pathologists who are not only experts in their fields, but who also contribute their own valuable insights making this new book an essential resource for practicing general and specialist surgical pathologists and pathologists in training.



Friday, May 18, 2012

Biochemistry and Molecular Biology of Parasites

Biochemistry and Molecular Biology of Parasites
J. Joseph Marr
ISBN-10: 012390899X
ISBN-13: 978-0123908995

The study of parasitic organisms at the molecular level has yielded fascinating new insights of great medical, social, and economical importance, and has pointed the way for the treatment and prevention of the diseases they cause. Biochemistry and Molecular Biology of Parasites presents an up-to-date account of this modern scientific discipline in a manner that allows and encourages the reader to place the biochemistry and molecular biology of these organisms in their biological context. The chapters are cross-referenced and grouped in an arrangement that provides a fully integrated whole, and permits the reader to create a composite of the biochemical function of these organisms. Individual chapter includes those devoted to metabolism, in both aerobic and anaerobic protozoa; antioxidant mechanisms; parasite surfaces; organelles; invasion mechanisms; and chemotherapy. The helminths are discussed not only from the point of view of their cellular biochemistry and metabolism, but also with respect to both their integrated functions such as neurochemistry, structure and functions of surfaces, and reproduction. Written by expert investigators, this book will be of interest to all experienced researchers, graduate students, and to the newcomer eager to become familiar with the biochemistry and molecular biology of parasites.



Monday, May 14, 2012

25 Years of p53 Research, 1st ed. 2007

25 Years of p53 Research
Pierre Hainaut and Klas G. Wiman
ISBN-10: 1402065647
ISBN-13: 978-1402065644

p53 has emerged as a key tumor suppressor and important target for novel cancer therapy. This book, written by world-leading p53 researchers including many of those who have shaped the field over the past 25 years, provides unique insights into the progress of the field and the prospects for better cancer diagnosis and therapy in the future.



Sunday, May 13, 2012

AJCC Cancer Staging Manual, 7th ed. 2010

AJCC Cancer Staging Manual
Stephen B. Edge, David R. Byrd, Carolyn C. Compton, April G. Fritz
ISBN-10: 0387884408
ISBN-13: 978-0387884400

The AJCC Cancer Staging Manual and Handbook, prepared by the American Joint Committee on Cancer, are used by physicians and health care professionals throughout the world to facilitate the uniform description and reporting of neoplastic diseases. Proper classification and staging is essential for the physician to assign proper treatment, evaluate results of management and clinical trials, and to serve as the standard for local, regional and international reporting on cancer incidence and outcome. The Seventh Edition of the AJCC Cancer Staging Manual brings together all the currently available information on staging of cancer at various anatomic sites and incorporates newly acquired knowledge on the etiology and pathology of cancer. As knowledge of cancer biology expands, cancer staging must incorporate these advances. The current revision provides evidence-based staging based upon the established tenets of TNM classification supplemented by selected molecular markers. Relevant markers supported by evidence and of sufficient impact for treatment decisions have been included to define stage, for example Gleason’s Score and PSA in prostate cancer.
Organized by disease site into 57 comprehensive chapters, the Seventh Edition features much-anticipated, major revisions to many chapters including breast, colon, prostate, kidney, and others. There are new primary site chapters for extrahepatic bile ducts, distal bile duct, cutaneous squamous cell carcinoma, Merkel cell carcinoma, and the adrenal gland plus a vastly expanded section on ophthalmologic malignancies.

User-friendly enhancements include:

  •  a revised and expanded presentation of the principles and rules of TNM staging
  • a concise summary of changes in the TNM classification and "Staging at a Glance" opening each chapter to provide a snapshot of staging and coding details
  • numerous new line drawings illustrating key sites throughout the text
  • full color text to highlight elements of TNM, stage groupings and prognostic factors
  • a revised user friendly "Staging Form"
  • a CD-ROM packaged with each Manual containing printable Staging Forms

The Seventh Editions of the AJCC Cancer Staging Manual and Handbook remain the essential references for oncologists, pathologists, surgeons, cancer registrars and medical professionals worldwide to ensure that all those taking care of cancer patients are fully versed in the language of cancer staging.



How the Immune System Works, 4th ed. 2012

How the immune system works 4th ed 2012
Lauren Sompayrac
ISBN-10: 0470657294
ISBN-13: 978-0470657294

How the Immune System Works is not a comprehensive textbook. It’s the book thousands of students have used to help them understand what’s in their big, thick, immunology texts. In this book, Dr. Sompayrac cuts through the jargon and details to reveal, in simple language, the essence of this complex subject.

Fifteen easy to follow lectures, featuring the uniquely popular humorous style and engaging analogies developed by Dr Sompayrac, provide an introduction to the ‘bigger picture’, followed by practical discussion on how each of the components interacts with one another.

Now featuring full-color diagrams, this book has been rigorously updated for its fourth edition to reflect today’s immunology teaching and includes updated discussion of B and T cell memory, T cell activation, vaccines, immunodeficiency, and cancer.

Whether you are completely new to immunology, or require a refresher, How the Immune System Works is an enjoyable way of engaging with the key concepts – you need know nothing of the workings of the immune system to benefit from this book!

How the Immune System Works is now accompanied by a FREE enhanced Wiley Desktop Edition - the interactive, digital version of the book - featuring downloadable text and images, highlighting and note taking facilities, book-marking, cross-referencing, in-text searching, and linking to references and glossary terms. It is also available from CourseSmart for instant, online and offline access for studying anytime, anywhere.



Saturday, May 5, 2012

Medical Microbiology and Infection: at a Glance, 4th ed. 2012

Medical Microbiology and Infection at a Glance
Stephen Gillespie and Kathleen Bamford
ISBN-10: 0470655712
ISBN-13: 978-0470655719

This concise and popular introduction to medical microbiology and infection encapsulates the fundamental facts and principles of this rapidly growing and changing subject area. Written by experienced clinicians and teachers, it covers the basic concepts of medical microbiology, and the main human pathogens and infectious syndromes, in an accessible and lucid format.
This fully updated fourth edition is now supported by a companion website at containing extra self-assessment cases, colour slides, further reading, and key point summaries.

Medical Microbiology and Infection at a Glance is an invaluable revision aid for medical and allied health students and junior doctors, and is ideal for anyone seeking a comprehensive and concise guide to this subject area.



Friday, May 4, 2012

Electron Microscopy Methods and Protocols


Electron Microscopy Methods and Protocols
Methods in Molecular Biology, vol. 117
N. Hajibagheri
Humana Press Inc.,



Thursday, May 3, 2012

Parasitology for Medical and Clinical Laboratory Professionals, 1st ed. 2012

Parasitology for Medical and Clinical Laboratory Professionals 2012
John W. Ridley
ISBN-10: 1435448162
ISBN-13: 978-1435448162

PARASITOLOGY FOR MEDICAL LABORATORY TECHNICIANS is the ideal text to guide readers in understanding the background, source, recovery, and identification of a well-representative range of organisms that commonly affect humans. This book organizes a complex set of topics into an understandable and easy-to-read format that will help readers learn more about parasitic infections and how to effectively collect and prepare samples, aiding in the diagnosis of parasitosis. The subtle differences between similar parasitic organisms are all explained in a simple and easily understood manner, increasing the likelihood that readers will be able to recover the parasites, prepare them for identification and, subsequently, ensure effective treatment.



Tuesday, May 1, 2012

Amyloid and Related Disorders: Surgical Pathology and Clinical Correlations, 2012

Amyloid and Related Disorders: Surgical Pathology and Clinical Correlations
(Current Clinical Pathology)
Maria M. Picken, Ahmet Dogan, Guillermo A. Herrera
ISBN-10: 1607613883
ISBN-13: 978-1607613886

Abnormal proteins have been known to be associated with various pathologies. Most notably, these involve amyloidoses, monoclonal protein deposits associated with plasma cell dyscrasia/multiple myeloma, cryoglobulins and various related organized deposits. Systemic Amyloid and Related Disorders presents an overview of recent developments in the area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies is also discussed. While the main portion of the text focuses on renal pathology, the involvement of other organ systems, such as cardiac, gastrointestinal and pulmonary pathology is also covered. This approach provides a unifying concept of these pathologic processes, which appear to have systemic involvement, and which have, hitherto, not been universally appreciated. Awareness of these diseases among a wider audience of pathologists may increase the rate of their diagnosis as well as that of earlier diagnosis. This volume will be invaluable to renal pathologists, cardiac pathologists, gastro-intestinal pathologists and general pathologists.


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